Vitamin 1.25 - (OH)2-D3 (calcitriol)
Vitamin 1.25-(OH)2-D3 is called calcitriol, biologically the most active form of vitamin D, also called D-hormone. It regulates the assimilation of calcium and phosphorus in the small intestine, bone mineralisation, and the synthesis and secretion of the parathyroid hormone (PTH). It is important for the formation and renewal of bones.
Vitamin D (D3 and D2), which is mostly produced in the skin when exposed to the sun, is a biologically inactive substance that is transformed into an active form in the body after passing through several stages.
First, in the liver, vitamin D is turned into 25-hidroxyvitamin D (25(OH)D) – calcifediol. In the next stage, in the kidneys, calcifediol is transformed into the active form of the vitamin – calcitriol. The activated vitamin acts through the vitamin D receptors (VDR) that are located on the cell nuclei membranes of various organs.
The decrease in calcitriol is the key indicator showing that vitamin D is not being assimilated properly (activated in the liver and kidneys) regardless of its adequate intake.
Prior registration is not required; upon arrival, please go straight to the reception.
Information on how to prepare for the test is available HERE.
Why it is worth
To be examined at our Centre?
- The laboratory is accredited with the ISO 15189 standard, so you can be confident that your tests will be performed to the highest quality.
- You will find out the results of the main tests within 1–2 hours and the rest within 1 day, except in cases where this is impossible due to the technological process (e.g., the time it takes for a culture to grow).
- The results of the tests carried out will be explained by our laboratory specialists. This service is only offered by a few laboratories in the country.
- If required, we can perform further tests using the same sample of blood, for up to 7 days after the sampling.
- No danger of damaging or mixing up the test samples due to transportation.
- Tests can be carried out anonymously.
Good to know
Who should have a calcitriol blood concentration test?
A calcitriol test can be carried out when renal function disorder is suspected or the deficiency of the enzyme that transforms the inactive form of vitamin D into the active form, generally for older people since the kidney function deteriorates with age even when a person does not have any renal diseases. Moreover, it can be recommended for children to confirm the diagnosis of rickets. In rare cases, this test can be carried out due to increased calcium concentration or when a person has certain diseases (sarcoidosis, lymphoma).
How to find out your test results?
- Your test results will be ready within 1 working day.
You can pick them up at the reception or, if you wish, we will email them.
- For an explanation of the test results, you should call the laboratory tel. (+370) 247 64 17.
What should you do if the test results indicate ionised calcium deviations from the norm?
Contact your family doctor or internist or register to visit a physician specialising in this field at our centre. Please find the prices for a consultation HERE.